As RandD productivity is declined and advancement times were lengthened, as clinical trials are becoming more complicated and costly there has been sharp rise in RandD expenditure. Social factors comprises doctor demographic and cultural features of doctor exterior macro atmosphere these factors effects customers needs and doctor size of abilities markets, some social elements come with health recognition, inhabitants growth rate, age distribution, emphasis on safety and provider attitudes. ageing populations are developing pressure on healthcare investment techniques as over 65 consumes four times greater than that of below 65 which leads medical more expensive generation solutions and augment in affected person expectations had created an unsustainable situation doctor industry. Some international locations cannot enjoy familiar coverage system and latest remedies because they are not funded by doctor insurance companies like USA which could afford latest generation but cannot share doctor blessings due to expanding populations in various parts of doctor world. In developed countries consumer are benefited by doctor insurance and can afford ethical drugs but doctor international locations who cannot afford medical moral drugs are switching medical established medical save coast which pressuring pharmacists medical alternative familiar drug as doctor first choice, patented drugs are just used if common drug fails. The OTCover doctor counter comprise of 20% of market which may purchase without prescription especially OTC is more in developing countries and also for these doctor patented drug businesses has introduce ailment control projects medical attack doctor demanding situations from customary.